BDBM50623920 CHEMBL5423656

SMILES [H][C@]1(Cc2ccccc2CN1)[C@H](O)CN1CCN(CC)c2cc(ccc2C1=O)C(=O)N1CCC2(CC(C2)OC)CC1

InChI Key InChIKey=BWPMFVYROSUWOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50623920   

TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50623920(CHEMBL5423656)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PRMT5 in human Z138 cells assessed as suppression of sDMA levelMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50623920(CHEMBL5423656)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed