BDBM50623921 CHEMBL5434784

SMILES CC(=O)N1CCC(CC1)Nc1cc(C(=O)N2CC[C@@H]([C@@H](O)C2)N2CCc3ccccc3C2)c(F)cn1

InChI Key InChIKey=RECPIUPJQVYMIJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50623921   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50623921(CHEMBL5434784)
Affinity DataEC50:  0.900nMAssay Description:Inhibition of full-length recombinant PRMT5/full-length recombinant MEP50 (unknown origin) expressed in baculovirus infected Sf21 cells using biotiny...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50623921(CHEMBL5434784)
Affinity DataEC50:  6.90nMAssay Description:Inhibition of PRMT5 in human MCF7 cells assessed as suppression of arginine sDMA incubated for 3 days by target engagement assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed