BDBM50624489 CHEMBL5399676

SMILES Cc1ccc(cc1)-c1cc2n(cc(C(=O)N3CCC(N)CC3)c2cc1-c1ccc(cc1)C#N)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=UFKPGWMKQUSRPU-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50624489   

TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624489(CHEMBL5399676)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human LSD1 using fluorometric substrate by HRP based fluorimeter microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624489(CHEMBL5399676)
Affinity DataKi:  155nMAssay Description:Inhibition of LSD1 (unknown origin) assessed as inhibition constant using H3K4me2 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624489(CHEMBL5399676)
Affinity DataIC50: 720nMAssay Description:Inhibition of recombinant MAO-B (unknown origin) incubated for 60 mins by luminescence based flow cytometryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624489(CHEMBL5399676)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of recombinant MAO-A (unknown origin) incubated for 60 mins by luminescence based flow cytometryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed