BDBM50624833 CHEMBL5410682

SMILES Oc1ccc(\C=C\C=C(/C#N)C(=O)N2CCCCC2)cc1O

InChI Key InChIKey=AURKHVWGDUMMNB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50624833   

TargetCatechol O-methyltransferase(Rat)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50624833(CHEMBL5410682)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of MB-COMT in rat brain homogenates using adrenaline as substrate and SAM as cofactor preincubated for 20 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCatechol O-methyltransferase(Rat)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50624833(CHEMBL5410682)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of MB-COMT in rat liver homogenates using adrenaline as substrate and SAM as cofactor preincubated for 20 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50624833(CHEMBL5410682)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of human MAO-B using kynuramine as substrate incubated for 30 mins by spectrophotometry analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed