BDBM50624896 CHEMBL5397460

SMILES [H][C@@]12COP(=O)(OCCSC(=O)C(C)(C)C)O[C@]3([H])C[C@H](O[C@@]3([H])COP(=O)(OCCSC(=O)C(C)(C)C)O[C@@]1([H])C[C@@H](O2)n1cnc2ncnc(N)c12)n1cnc2ncnc(N)c12

InChI Key InChIKey=JACGZEJSYCJGIA-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50624896   

TargetStimulator of interferon genes protein(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50624896(CHEMBL5397460)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at STING in human THP-1 reporter cells incubated for 4 hrs in presence of lipofectamine 2000 by QUANTI-Luc assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50624896(CHEMBL5397460)
Affinity DataEC50:  5.20nMAssay Description:Agonist activity at STING in human THP-1 reporter cells incubated for 24 hrs by QUANTI-Luc assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50624896(CHEMBL5397460)
Affinity DataEC50:  6.20nMAssay Description:Agonist activity at STING in PMA-treated human THP-1 reporter cells incubated for 30 mins in presence of digitonin by QUANTI-Luc assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed