BDBM50625079 CHEMBL5419243

SMILES CC[N+](CC)(CCCCCn1c(=O)cc(C)n(CCCCCCn2c(C)cc(=O)n(C)c2=O)c1=O)Cc1ccccc1C(F)(F)F

InChI Key InChIKey=RDSIJVSRSNHGQF-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50625079   

TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625079(CHEMBL5419243)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625079(CHEMBL5419243)
Affinity DataKi:  150nMAssay Description:Mixed competitive inhibition of human AChE assessed as inhibition of constant by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625079(CHEMBL5419243)
Affinity DataKi:  430nMAssay Description:Mixed uncompetitive inhibition of human AChE assessed as inhibition of constant by cornish-bowden plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625079(CHEMBL5419243)
Affinity DataKi:  3.50E+4nMAssay Description:Mixed competitive inhibition of human BChE assessed as inhibition of constant by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625079(CHEMBL5419243)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed