BDBM50625746 CHEMBL5413772

SMILES CC[C@H](C)Nc1cc(Nc2ccnc(n2)-c2cnn(c2)S(=O)(=O)C2CC2)ncc1C(=O)CC

InChI Key InChIKey=YJHQKHRGRXRQHB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50625746   

TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50625746(CHEMBL5413772)
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) phosphorylationMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50625746(CHEMBL5413772)
Affinity DataIC50: 13nMAssay Description:Inhibition of EGFR Del19/T790M/C797S mutant (unknown origin) phosphorylationMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50625746(CHEMBL5413772)
Affinity DataIC50: 212nMAssay Description:Inhibition of wild-type EGFR (unknown origin) phosphorylationMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed