BDBM50625747 CHEMBL5415774

SMILES CCNS(=O)(=O)c1cnc(Nc2ccnc(n2)-c2cnn(c2)S(=O)(=O)C2CC2)cc1N[C@@H](C)CC

InChI Key InChIKey=HWMQDRPRVMUNDD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50625747   

TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50625747(CHEMBL5415774)
Affinity DataIC50: 4.88E+3nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) phosphorylationMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50625747(CHEMBL5415774)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of wild-type EGFR (unknown origin) phosphorylationMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50625747(CHEMBL5415774)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of EGFR Del19/T790M/C797S mutant (unknown origin) phosphorylationMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed