BDBM50625761 CHEMBL5438848

SMILES COc1cc(\C=C2\NC(=O)N(Cc3ccc(C)cc3)C2=O)ccc1OCc1cccc(c1)C(O)=O

InChI Key InChIKey=MDVFJSDGXRDOQF-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50625761   

TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
The Affiliated Hospital of Yangzhou University

Curated by ChEMBL
LigandPNGBDBM50625761(CHEMBL5438848)
Affinity DataKi:  900nMAssay Description:Competitive inhibition of recombinant human ACP1 using pNPP as substrate assessed as inhibition constant preincubated with compound for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
The Affiliated Hospital of Yangzhou University

Curated by ChEMBL
LigandPNGBDBM50625761(CHEMBL5438848)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human ACP1 using pNPP as substrate preincubated with compound for 10 mins followed by substrate addition and measured by ab...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
The Affiliated Hospital of Yangzhou University

Curated by ChEMBL
LigandPNGBDBM50625761(CHEMBL5438848)
Affinity DataKi:  2.80E+3nMAssay Description:Competitive inhibition of recombinant human PTP1B using pNPP as substrate assessed as inhibition constant preincubated with compound for 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
The Affiliated Hospital of Yangzhou University

Curated by ChEMBL
LigandPNGBDBM50625761(CHEMBL5438848)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate preincubated with compound for 10 mins followed by substrate addition and measured by a...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
The Affiliated Hospital of Yangzhou University

Curated by ChEMBL
LigandPNGBDBM50625761(CHEMBL5438848)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of recombinant human TCPTPMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
The Affiliated Hospital of Yangzhou University

Curated by ChEMBL
LigandPNGBDBM50625761(CHEMBL5438848)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant human CD45More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed