BDBM50625897 CHEMBL5399772

SMILES CNS(=O)(=O)Cc1cc(Cl)cc(c1)-c1c2CCN([C@@H](C)c2nn1C)C(=O)c1cccc(OC)c1Cl

InChI Key InChIKey=CDJVZDRSWJUSDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50625897   

TargetMonoglyceride lipase(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50625897(CHEMBL5399772 | US20250059185, Example 3)
Affinity DataIC50: 63nMAssay Description:Inhibition of MAGL (unknown origin) using 2-arachidonoylglycerol as substrate preincubated with compound for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMonoglyceride lipase(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50625897(CHEMBL5399772 | US20250059185, Example 3)
Affinity DataIC50: 63nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent