BDBM50625921 CHEMBL5409958

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(c2c(NCc3ccccc3)ncnc12)C(F)(F)F

InChI Key InChIKey=HKPIERLZGGUUMI-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50625921   

Target5-hydroxytryptamine receptor 2B(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625921(CHEMBL5409958)
Affinity DataKi:  500nMAssay Description:Inhibition of human 5-HT2B receptor assessed as inhibition constant by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625921(CHEMBL5409958)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human 5-HT6 receptor assessed as inhibition constant by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625921(CHEMBL5409958)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human KOR assessed as inhibition constant by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625921(CHEMBL5409958)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human alpha 2C adrenergic receptor assessed as inhibition constant by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625921(CHEMBL5409958)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of human sigma 1 receptor assessed as inhibition constant by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed