BDBM50625941 CHEMBL5435446

SMILES [H][C@@]12Cc3ccccc3-c3c(OC)c(OC)cc(CCN1C(=O)c1cc[n+](Cc4ccccc4Cl)cc1)c23

InChI Key InChIKey=IISVIQHACVXRIA-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50625941   

TargetAcetylcholinesterase(Electric eel)
Chulabhorn Research Institute

Curated by ChEMBL
LigandPNGBDBM50625941(CHEMBL5435446)
Affinity DataIC50: 60nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Chulabhorn Research Institute

Curated by ChEMBL
LigandPNGBDBM50625941(CHEMBL5435446)
Affinity DataKi:  220nMAssay Description:Binding affinity to electric eel AChE assessed as inhibition constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Chulabhorn Research Institute

Curated by ChEMBL
LigandPNGBDBM50625941(CHEMBL5435446)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed