BDBM50625985 CHEMBL5431731

SMILES CN1Cc2cc(ccc2C1=O)-c1cc(F)cc2CN([C@@H](C(C)(C)O)C(F)(F)F)C(=O)c12

InChI Key InChIKey=WVUGIJUDANWNRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50625985   

TargetCeramide glucosyltransferase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50625985(CHEMBL5431731)
Affinity DataIC50: 50nMAssay Description:Inhibition of GCS in human A-375 cell golgi body preparations using ceramide and UDP-glucose as substrate by UDP-Glo based luminometric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50625985(CHEMBL5431731)
Affinity DataIC50: 60nMAssay Description:Inhibition of GCS in wild type HDF cells by LC-MS assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed