BDBM50626276 CHEMBL5198469

SMILES CNS(=O)(=O)c1ccc(Nc2ccc(cc2)C(F)(F)F)c(c1)-c1cn(C)cn1

InChI Key InChIKey=LLCVDQHLYHBAHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50626276   

TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50626276(CHEMBL5198469)
Affinity DataIC50: 1nMAssay Description:Inhibition of YAP (unknown origin) incubated for 24 hrs by Promega Dual-Luciferase Reporter AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM50626276(CHEMBL5198469)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal His-tagged TEAD1 (unknown origin) (209 to 426 residues) expressed in Escherichia coli BL21 by chromatography analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details