BDBM50626418 CHEMBL5419132

SMILES O=C1CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CCN1

InChI Key InChIKey=NYJFLKFMMFVJNM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50626418   

TargetKappa-type opioid receptor(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50626418(CHEMBL5419132)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human KOR expressed in HEK293 cells assessed as inhibition constant incubated for 90 mins by liquid scintillation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50626418(CHEMBL5419132)
Affinity DataKi: >10nMAssay Description:Binding affinity to human DOR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50626418(CHEMBL5419132)
Affinity DataKi: >10nMAssay Description:Binding affinity to human KOR expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed