BDBM50627086 CHEMBL5425184

SMILES COc1cc2CCN(C)Cc2cc1Nc1ncc(C(N)=O)c(Nc2cccc3CCOc23)n1

InChI Key InChIKey=MXIFTWCOJMYHBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50627086   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50627086(CHEMBL5425184)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human HPK1 catalytic domain (1 to 346 residues) using His-tagged SLP76 as substrate assessed as reduction in substrate phosphorylation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed