BDBM50627088 CHEMBL5424247

SMILES CCOc1ccccc1Nc1nc(Nc2cc3CN(C)CCc3cc2OC)ncc1C(N)=O

InChI Key InChIKey=ISFJBCHVYJQBFS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50627088   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50627088(CHEMBL5424247)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human HPK1 catalytic domain (1 to 346 residues) using His-tagged SLP76 as substrate assessed as reduction in substrate phosphorylation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed