BDBM50627098 CHEMBL5397160

SMILES CN1CCC(NC(=O)OCC#Cc2cc(F)c(OCc3nnc(S[C@@H]4C=CCCC4)n3-c3cccnc3)cc2F)CC1

InChI Key InChIKey=YBCFFJLDKVTSPF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50627098   

TargetTransitional endoplasmic reticulum ATPase(Human)
University of Pittsburgh Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627098BDBM50627098(CHEMBL5397160)
Affinity DataIC50: 15nMAssay Description:Inhibition of p97 (unknown origin) ATPase activity by Biomol Green Reagent based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTransitional endoplasmic reticulum ATPase(Human)
University of Pittsburgh Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627098BDBM50627098(CHEMBL5397160)
Affinity DataEC50:  2.70E+3nMAssay Description:Inhibition of p97 in human HeLa cells expressing UbG76V-GFP/ODD-Luc assessed as accumulation of Ub-GFP incubated for 6 hrs by confocal microscopic an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed