BDBM50627099 CHEMBL5408449

SMILES Cn1c2ccccc2c(N2CCN(CC2)C(c2ccccc2)c2ccccc2)c([N+]([O-])=O)c1=O

InChI Key InChIKey=XIVOLEKHEMYRBO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50627099   

TargetDiacylglycerol kinase alpha(Human)
Bristol Myers Squibb Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50627099(CHEMBL5408449)
Affinity DataIC50: 15nMAssay Description:Inhibition of human DGK alpha using 1, 2-Dilauroyl-sn-glycerol as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDiacylglycerol kinase gamma(Human)
Bristol Myers Squibb Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50627099(CHEMBL5408449)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human DGK gamma using 1, 2-Dilauroyl-sn-glycerol as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDiacylglycerol kinase beta(Human)
Bristol Myers Squibb Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50627099(CHEMBL5408449)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human DGK beta using 1, 2-Dilauroyl-sn-glycerol as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDiacylglycerol kinase zeta(Human)
Bristol Myers Squibb Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50627099(CHEMBL5408449)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DGK zeta using 1, 2-Dilauroyl-sn-glycerol as substrate by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDiacylglycerol kinase kappa(Homo sapiens)
Bristol Myers Squibb Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50627099(CHEMBL5408449)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DGK kappa using 1, 2-Dilauroyl-sn-glycerol as substrate by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDiacylglycerol kinase iota(Homo sapiens)
Bristol Myers Squibb Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50627099(CHEMBL5408449)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DGK iota using 1, 2-Dilauroyl-sn-glycerol as substrate by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed