BDBM50627100 CHEMBL5402920

SMILES Cn1c2ccc(cc2c(N2CCN(CC2)C(c2ccc(F)cc2)c2ccc(F)cc2)c([N+]([O-])=O)c1=O)C#N

InChI Key InChIKey=XFGAEPAEOOTMIR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50627100   

TargetDiacylglycerol kinase alpha(Human)
Bristol Myers Squibb Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50627100(CHEMBL5402920)
Affinity DataIC50: 34nMAssay Description:Inhibition of human DGK alpha using 1, 2-Dilauroyl-sn-glycerol as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDiacylglycerol kinase iota(Homo sapiens)
Bristol Myers Squibb Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50627100(CHEMBL5402920)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human DGK iota using 1, 2-Dilauroyl-sn-glycerol as substrate by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDiacylglycerol kinase zeta(Human)
Bristol Myers Squibb Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50627100(CHEMBL5402920)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DGK zeta using 1, 2-Dilauroyl-sn-glycerol as substrate by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed