BDBM50627118 CHEMBL5440854

SMILES O=C1N(CC[Se][Se]CCN2C(=O)c3ccccc3C2=O)C(=O)c2ccccc12

InChI Key InChIKey=IMZXETXDVAKDSY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50627118   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50627118(CHEMBL5440854)
Affinity DataIC50: 400nMAssay Description:Negative allosteric modulator activity at human wildtype KGA incubated for 5 hrs in presence of GDH and NADP by EZMTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThioredoxin reductase(Escherichia coli (strain K12))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50627118(CHEMBL5440854)
Affinity DataIC50: 700nMAssay Description:Negative allosteric modulator activity at Escherichia coli TrxR using DTNB as substrate preincubated for 20 mins followed by substrate addition in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50627118(CHEMBL5440854)
Affinity DataIC50: 2.10E+3nMAssay Description:Negative allosteric modulator activity at human wildtype KGA using glutamine as substrate preincubated for 1 hr followed by substrate addition in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed