BDBM50627126 CHEMBL5428784
SMILES C[C@H](NC1(C)CCC1)c1cc2C(=O)N(Cc2c(Cl)c1)c1cccc(c1)[C@@]1(C[C@H](F)C1)c1nncn1C
InChI Key InChIKey=OHIWAMBAFXDJCL-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50627126
Affinity DataKd: 2nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of biotin-tagged Cbl-b (unknown origin) assessed as reduction in LCK ubiquitination using His-LCK as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Affinity DataKd: 28nMAssay Description:Table 4: Chaser assay utilize a single cycle kinetics SPR experiment with a contact time of 120 seconds, a flow rate of 50 μl/min and a dissociation ...More data for this Ligand-Target Pair