BDBM50627165 CHEMBL5394673

SMILES FC(F)(F)Oc1ccc2nc(sc2c1)N1CCNCC1

InChI Key InChIKey=IFWQLRCODRPXKE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50627165   

TargetSodium channel protein type 9 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627165(CHEMBL5394673)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human Nav 1.7 expressed in HEK293T cells assessed as phasic block at 10 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627165(CHEMBL5394673)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as phasic block at 10 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627165(CHEMBL5394673)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of human Nav 1.7 expressed in HEK293T cells assessed as tonic block at 0.1 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50627165(CHEMBL5394673)
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of human Nav 1.4 expressed in HEK293T cells assessed as tonic block at 0.1 Hz by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed