BDBM50627198 CHEMBL5402950

SMILES Cn1nc2cc1CCc1cc(c3ccc(F)cc3c1)OCCCc1c(C(=O)O)[nH]c3c(c(Cl)ccc13)-c1c(cnn1C)CSC2

InChI Key InChIKey=PBTFWRZKWTXEKX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50627198   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627198BDBM50627198(CHEMBL5402950)
Affinity DataKi:  0.0470nMAssay Description:Displacement of Cy5-labeled BIM BH3 peptide (H3N-(C/Cy5Mal)-WIAQELRRIGDEFN-OH) from MCL-1 (unknown origin) assessed as inhibition constant incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed