BDBM50627713 CHEMBL5400606

SMILES N[C@@H](CC(=O)N(CC#Cc1cccc(c1)C(N)=O)C[C@H]1C[C@H]([C@H](O)[C@@H]1O)n1ccc2c(Cl)ncnc12)C(O)=O

InChI Key InChIKey=ZQGPIBRLGHFZBM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50627713   

TargetNicotinamide N-methyltransferase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50627713(CHEMBL5400606)
Affinity DataKi:  49nMAssay Description:Binding affinity to full-length recombinant human NNMT expressed in Escherichia coli BL21(DE3) cells assessed as inhibition constant preincubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNicotinamide N-methyltransferase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50627713(CHEMBL5400606)
Affinity DataIC50: 87nMAssay Description:Inhibition of full-length recombinant human NNMT expressed in Escherichia coli BL21(DE3) cells using nicotinamide as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed