BDBM50627890 CHEMBL5422577

SMILES NCCCCCCNC(=O)c1ccc(NC(=O)c2ccc(CN(C3CC3)C(=O)c3ccc4NC(=O)COc4c3)cc2)cc1

InChI Key InChIKey=MDIKJIFCQAJLPD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50627890   

TargetHistone-lysine N-methyltransferase NSD2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50627890(CHEMBL5422577)
Affinity DataKd:  24nMAssay Description:Binding affinity to NSD2 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50627890(CHEMBL5422577)
Affinity DataEC50:  350nMAssay Description:Induction of degradation of NSD2 in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed