BDBM50628030 CHEMBL5415069

SMILES [H][C@@]12C[C@]1([H])c1c(C2)c(nn1C(=O)N1CCN2CCC1CC2)-c1cnc(OC)c(Cl)c1

InChI Key InChIKey=NWUCNVFCOCMZNQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628030   

TargetCeramide glucosyltransferase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50628030(CHEMBL5415069 | US20250026762, Compound 8)
Affinity DataEC50:  0.100nMAssay Description:Inhibition of GCS in human A-375 cell golgi body using C6-ceramide and UDP-glucose as substrate assessed as reduction in UDP production preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCeramide glucosyltransferase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50628030(CHEMBL5415069 | US20250026762, Compound 8)
Affinity DataEC50:  0.100nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent