BDBM50628270 CHEMBL5434080

SMILES OC(=O)c1ccc2cccc(NS(=O)(=O)c3ccc(cc3[N+]([O-])=O)C(F)(F)F)c2n1

InChI Key InChIKey=WGYJUNSCNPKAQX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628270   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Freie University Berlin

Curated by ChEMBL
LigandPNGBDBM50628270(CHEMBL5434080)
Affinity DataIC50: 370nMAssay Description:Inhibition of C-terminal 6His-tagged full length NDM-1 (unknown origin) expressed in Escherichia coli BL21-DE3 using nitrocefin as substrate incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Freie University Berlin

Curated by ChEMBL
LigandPNGBDBM50628270(CHEMBL5434080)
Affinity DataKi:  600nMAssay Description:Binding affinity to human recombinant MMP-2 CD assessed as inhibition constant using OMNIMMP as substrate incubated for 30 mins by fluorescence based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed