BDBM50628342 CHEMBL4748288

SMILES CC1(CC1)Oc1ccc2[nH]nc(-c3cc(ncn3)N3CCN(CC3)C(=O)CCOCCNc3cccc4CN(C5CCC(=O)NC5=O)C(=O)c34)c2c1

InChI Key InChIKey=DGDUMVWFYAQVQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628342   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50628342(CHEMBL4748288)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant (970 to 2527 residues) expressed in insect cells using LRRKtide as substrate measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50628342(CHEMBL4748288)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in insect cells using LRRKtide as substrate measured after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed