BDBM50628344 CHEMBL5429152

SMILES CC1(CC1)Oc1ccc2[nH]nc(-c3cc(ncn3)N3CCN(CC3)C(=O)CCOCCOCCNc3cccc4C(=O)N(C5CCCNC5=O)C(=O)c34)c2c1

InChI Key InChIKey=DFBXATAQNVOAEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628344   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50628344(CHEMBL5429152)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant (970 to 2527 residues) expressed in insect cells using LRRKtide as substrate measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50628344(CHEMBL5429152)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in insect cells using LRRKtide as substrate measured after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed