BDBM50628349 CHEMBL5411054

SMILES C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCC(=O)N1CCN(CC1)c1cc(ncn1)-c1n[nH]c2ccc(OC3(C)CC3)cc12)C(C)(C)C)c1ccc(cc1)-c1scnc1C

InChI Key InChIKey=ALDLVHMDSBEBKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628349   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50628349(CHEMBL5411054)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in insect cells using LRRKtide as substrate measured after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50628349(CHEMBL5411054)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant (970 to 2527 residues) expressed in insect cells using LRRKtide as substrate measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed