BDBM50628375 CHEMBL5434338

SMILES NC(=O)c1c(Nc2ccc(N3CCOCC3)c(CO)c2)nc(NCc2ccc(Cl)c(NC(=O)C=C)c2)n2ccnc12

InChI Key InChIKey=DTDSWZCNBJHUFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628375   

TargetTyrosine-protein kinase ZAP-70(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628375(CHEMBL5434338)
Affinity DataIC50: 31nMAssay Description:Inhibition of ZAP-70 (unknown origin) using ULight-TK peptide as substrate incubated for 120 mins in presence of ATP by Lance Ultra Kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628375(CHEMBL5434338)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of SYK (unknown origin) using ULight-TK peptide as substrate incubated for 120 mins in presence of ATP by Lance Ultra Kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed