BDBM50628450 CHEMBL5405825

SMILES COc1ccc(cc1F)-c1nn([C@@H](C)c2nn(-c3cccnc3)c3cc(Cl)ccc23)c2ncnc(N)c12

InChI Key InChIKey=ZNCDEDBKQOCMSJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628450   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Zhejiang University

Curated by ChEMBL

LigandBDBM50628450(CHEMBL5405825)Copy SMILESCopy InChI

Affinity DataIC50: 0.800nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate in presence of ATP measured after 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/19/2024
Entry Details
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Zhejiang University

Curated by ChEMBL

LigandBDBM50628450(CHEMBL5405825)Copy SMILESCopy InChI

Affinity DataKd:  85nMAssay Description:Binding affinity to PI3Kdelta (unknown origin) assessed as dissociation constant by microscale thermophoresis assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/19/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL