BDBM50628611 CHEMBL5406873

SMILES COc1ccc(-c2cc(nn2C)C(=O)N[C@H]2CCCN(C)C2)c(Cl)c1

InChI Key InChIKey=QLOHOGRMRUDDPM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50628611   

LigandPNGBDBM50628611(CHEMBL5406873)
Affinity DataIC50: 657nMAssay Description:Antagonist activity at human alpha4/beta2 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50628611(CHEMBL5406873)
Affinity DataIC50: 2.56E+3nMAssay Description:Antagonist activity at human alpha3/beta4 nAChR expressed in HEK293 cells assessed as nicotine-induced intracellular calcium release incubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Cerevance

Curated by ChEMBL
LigandPNGBDBM50628611(CHEMBL5406873)
Affinity DataIC50: 4.47E+4nMAssay Description:Binding affinity to human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed