BDBM50628622 CHEMBL5439214

SMILES Cc1nc(NC(=O)N2C[C@@H](C[C@H]2C(N)=O)NS(=O)(=O)Cc2ccc(cc2)C(=O)NO)sc1-c1ccnc(c1)C(C)(C)C(F)(F)F

InChI Key InChIKey=PLBBMNVLYUEPKQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50628622   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Zhejiang Chinese Medical University

Curated by ChEMBL
LigandPNGBDBM50628622(CHEMBL5439214)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of PI3K alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhejiang Chinese Medical University

Curated by ChEMBL
LigandPNGBDBM50628622(CHEMBL5439214)
Affinity DataIC50: 26nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Zhejiang Chinese Medical University

Curated by ChEMBL
LigandPNGBDBM50628622(CHEMBL5439214)
Affinity DataIC50: 42nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Zhejiang Chinese Medical University

Curated by ChEMBL
LigandPNGBDBM50628622(CHEMBL5439214)
Affinity DataIC50: 285nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Zhejiang Chinese Medical University

Curated by ChEMBL
LigandPNGBDBM50628622(CHEMBL5439214)
Affinity DataIC50: 586nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Zhejiang Chinese Medical University

Curated by ChEMBL
LigandPNGBDBM50628622(CHEMBL5439214)
Affinity DataIC50: 880nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Zhejiang Chinese Medical University

Curated by ChEMBL
LigandPNGBDBM50628622(CHEMBL5439214)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhejiang Chinese Medical University

Curated by ChEMBL
LigandPNGBDBM50628622(CHEMBL5439214)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed