BDBM50628740 CHEMBL5402865

SMILES NC1(COC1)c1ccc(cc1)-c1nc(nc2c1CCC2(F)F)N1CC[C@@H]1C(F)(F)F

InChI Key InChIKey=AMRGISYBQNOYDB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50628740   

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM50628740(CHEMBL5402865 | US12410160, Example 696)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM50628740(CHEMBL5402865 | US12410160, Example 696)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of KHK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandPNGBDBM50628740(CHEMBL5402865 | US12410160, Example 696)
Affinity DataIC50: 1nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent