BDBM50629110 CHEMBL5409119

SMILES CCN(CC)C(=O)CSC(=S)N1CCN(CC1)c1cc(nc(n1)-n1c(nc2c(OC)cccc12)C(F)F)N1CCOCC1

InChI Key InChIKey=QTTKUYIEQUJVAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50629110   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629110(CHEMBL5409119)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of N-terminal GST-fused full-length human PI3Kalpha (1 to 1068 residues) expressed in baculovirus expression system using PIP2 as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed