BDBM50629267 CHEMBL5406146

SMILES Fc1ccc(cc1F)[C@@H]1CCNC[C@H]1NC(=O)c1cc-2c(OCCn3ncc(Br)c-23)s1

InChI Key InChIKey=YEYGCAOMGAHTST-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50629267   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629267(CHEMBL5406146)
Affinity DataIC50: 0.0230nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629267(CHEMBL5406146)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed