BDBM50629426 CHEMBL5400489

SMILES CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(OC)cc1

InChI Key InChIKey=OXWILHPCXGMGNW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50629426   

TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629426(CHEMBL5400489)
Affinity DataEC50:  232nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629426(CHEMBL5400489)
Affinity DataEC50:  1.83E+3nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Binghamton University School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50629426(CHEMBL5400489)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at TLR7 in HEK-Blue hTLR7 cells expressing NF-kappaB/AP-1 inducible SEAP assessed as increase in SEAP activity incubated for 24 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed