BDBM50629484 CHEMBL5417078

SMILES [H][C@@]12CN(CCN1CC1=C(CC(C)(C)C[C@@]1([H])OCCCOC2)c1ccc(Cl)cc1)c1ccc(C(=O)NS(=O)(=O)c2ccc(NC[C@H]3CC[C@@](C)(O)CC3)c(c2)[N+]([O-])=O)c(c1)N1CCCOc2nc3[nH]ccc3cc12

InChI Key InChIKey=OHTSOHPEJKZMRQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50629484   

TargetApoptosis regulator Bcl-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50629484(CHEMBL5417078)
Affinity DataKi:  0.0610nMAssay Description:Inhibition of human Bcl-2 expressed in Escherichia coli BL21(DE3) T1R cells preincubated under shaking condition for 1 min and measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50629484(CHEMBL5417078)
Affinity DataKi:  11nMAssay Description:Inhibition of human Bcl-xL expressed in Escherichia coli BL21(DE3) T1R cells preincubated under shaking condition for 1 min and measured after 3 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed