BDBM50629527 CHEMBL5419478

SMILES Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(N4CCN(CCNC(=O)C56CC7CC(CC(C7)C5)C6)CC4)nc3)cc3c2cnn3C(C)C)c(=O)[nH]1

InChI Key InChIKey=GOGPMXZRBPPKML-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50629527   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Xinxiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629527BDBM50629527(CHEMBL5419478)
Affinity DataIC50: 120nMAssay Description:Inhibition of EZH2 (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition and measured after 4 hrs by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed