BDBM50629806 CHEMBL5432835

SMILES Cn1cc(cn1)-c1cccc(n1)C(=O)Nc1cc(ncc1C(F)(F)F)N1CCC(C1)C(C)(C)O

InChI Key InChIKey=HRRUGRNBEPWHFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50629806   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629806(CHEMBL5432835)
Affinity DataIC50: 1nMAssay Description:Inhibition of GST20-tagged human LRRK2 using ERM as substrate measured after 90 mins in presence of ATP by lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629806(CHEMBL5432835)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GST20-tagged human LRRK2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629806(CHEMBL5432835)
Affinity DataIC50: 63nMAssay Description:Inhibition of CLK2 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed