BDBM50630155 CHEMBL5410192

SMILES CS(=O)(=O)NCC(Nc1ncc(cn1)-c1nnc(o1)C(F)F)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=RJVSECRBBVXPCQ-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50630155   

TargetHistone deacetylase 6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630155(CHEMBL5410192)
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant HDAC6 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630155(CHEMBL5410192)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant HDAC4 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630155(CHEMBL5410192)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant HDAC9 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630155(CHEMBL5410192)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant HDAC7 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630155(CHEMBL5410192)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC3 incubated for 10 mins by Spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630155(CHEMBL5410192)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC11 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630155(CHEMBL5410192)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC8 incubated for 60 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630155(CHEMBL5410192)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC1 incubated for 15 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630155(CHEMBL5410192)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC2 incubated for 15 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630155(CHEMBL5410192)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC5 incubated for 30 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50630155(CHEMBL5410192)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC10 incubated for 45 mins by fluorimetry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed