BDBM50630201 CHEMBL5434141

SMILES Cc1ccc(s1)-c1csc(NC(=O)CSc2nc3nccnc3c(=O)n2CCc2ccccc2)n1

InChI Key InChIKey=JNPNSKVAKUJWMI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630201   

TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Leibniz-Fmp

Curated by ChEMBL

LigandBDBM50630201(CHEMBL5434141 | US12247029, Entry 30)Copy SMILESCopy InChI

Affinity DataIC50: 420nMAssay Description:Inhibition of PI3KC2alpha deltaN domain (unknown origin) preincubated for 5 mins followed by substrate addition and measured after 20 mins in the pre...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/20/2024
Entry Details
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TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Leibniz-Fmp

Curated by ChEMBL

LigandBDBM50630201(CHEMBL5434141 | US12247029, Entry 30)Copy SMILESCopy InChI

Affinity DataIC50: 5.80E+3nMAssay Description:ADP-Glo kinase assay was performed as described by the manufacturer's protocol. Briefly, the kinase assay was performed with a 5 mixture of liver...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/15/2025
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL