BDBM50630242 CHEMBL5421933

SMILES Fc1ccc(Cn2c3ccccc3c(=O)[nH]c2=O)cc1C(=O)N1CCN(CC(F)(F)F)C(=O)C1

InChI Key InChIKey=VXXHFHBGNMSWMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630242   

TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50630242(CHEMBL5421933)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant PARP2 expressed in Escherichia coli BL21(DE3) incubated for 1 hr by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50630242(CHEMBL5421933)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human recombinant PARP1 expressed in Escherichia coli BL21(DE3) incubated for 1 hr by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed