BDBM50630395 CHEMBL5398246

SMILES Cc1cc2c(OCCOCCOc3cccc4nc(N)ccc34)cccc2nc1N

InChI Key InChIKey=OSVQUEULQAWXNT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630395   

TargetNeutrophil cytosol factor 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50630395(CHEMBL5398246)
Affinity DataKi:  1.22E+3nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetCytochrome b-245 heavy chain(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50630395(CHEMBL5398246)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of NOX-2 dependent superoxide generation in PMA-differentiated human PLB-985 cells incubated for 1 hr by WST-1 based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed