BDBM50630403 CHEMBL5429601

SMILES Cc1ccc(OCCOCCOc2cccc3nc(N)ccc23)c2ccc(N)nc12

InChI Key InChIKey=HPBAXSQAKLNUAA-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630403   

TargetNeutrophil cytosol factor 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50630403(CHEMBL5429601)
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of Cy5-labeled p22phox (149 to 162 residues) probe binding to His-tagged human p47phox (151 to 286 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetCytochrome b-245 heavy chain(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50630403(CHEMBL5429601)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of NOX-2 dependent superoxide generation in PMA-differentiated human PLB-985 cells incubated for 1 hr by WST-1 based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed