BDBM50630746 CHEMBL5394891

SMILES Cc1ncc(-c2ncc3N(C4CCOCC4)C(=O)[C@]4(C)COCCN4c3n2)c2cc[nH]c12

InChI Key InChIKey=PQWPFGHFJVFZRW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50630746   

TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50630746(CHEMBL5394891)
Affinity DataIC50: 48nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed