BDBM50630926 CHEMBL5411270

SMILES CN\C(N[C@H]1C[C@@H](C1)Nc1cc(nc2ccnn12)C(C)C)=N/C#N

InChI Key InChIKey=JHWGSBPTDRHUTQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50630926   

LigandPNGBDBM50630926(CHEMBL5411270)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CDK9/Cyclin T1 preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630926(CHEMBL5411270)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human CDK1/Cyclin A preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630926(CHEMBL5411270)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human CDK3/Cyclin E preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630926(CHEMBL5411270)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human CDK4/Cyclin D1 preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630926(CHEMBL5411270)
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of human CDK2/Cyclin A preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630926(CHEMBL5411270)
Affinity DataIC50: 6.07E+3nMAssay Description:Inhibition of human CDK5/P25 preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed