BDBM50630940 CHEMBL5396123

SMILES CC(C)Cc1cc(N[C@H]2CC[C@H](N)C2)n2nccc2n1

InChI Key InChIKey=HVERIWOPBLJMDS-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50630940   

LigandPNGBDBM50630940(CHEMBL5396123)
Affinity DataIC50: 21nMAssay Description:Inhibition of human CDK9/Cyclin T1 preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630940(CHEMBL5396123)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of human CDK4/Cyclin D1 preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630940(CHEMBL5396123)
Affinity DataIC50: 7.66E+3nMAssay Description:Inhibition of human CDK3/Cyclin E preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630940(CHEMBL5396123)
Affinity DataIC50: 9.47E+3nMAssay Description:Inhibition of human CDK2/Cyclin A preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630940(CHEMBL5396123)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CDK7/Cyclin H preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630940(CHEMBL5396123)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CDK6/Cyclin D1 preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630940(CHEMBL5396123)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CDK1/Cyclin A preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Kronos Bio

Curated by ChEMBL
LigandPNGBDBM50630940(CHEMBL5396123)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CDK8/Cyclin C preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
LigandPNGBDBM50630940(CHEMBL5396123)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CDK5/P25 preincubated for 20 mins followed by 32P-ATP addition and measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed